Digitonin from Cayman Chemical

Product Specs
ItemDigitonin
CompanyCayman Chemical
Price Pricing Info Supplier Page View Company Product Page
Catalog Number14952
Quantity250 mg
FormatA crystalline solid
Molecular Weight1229.3
ApplicationsSample Preparation

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Cayman Chemical

Cayman Chemical Company 1180 East Ellsworth Road

Ann Arbor, Michigan 48108

United States

Phone: (800) 364-9897
(734) 971-3640

Company Profile

Website: http://www.caymanchem.com/

(1) Positive and negative allosteric modulation of GluK2 kainate receptors by BPAM344 and antiepileptic perampanelCell ReportsFebruary 21, 2023Shanti Pal Gangwar, Laura Y. Yen, Maria V. Yelshanskaya, Alexander I. SobolevskyTechnologies,Cat# HCT-0020 Desthiobiotin,Sigma,Cat# D1411 Digitonin,Cayman Chemical Company,Cat# 14952 Perampanel,Cayman,Cat# 23003 BPAM344,AOBIOUS,Cat# AOB12707 DNQX dosodium salt,Tocris,Cat# 2312 Fetal

(2) Opening of glutamate receptor channel to subconductance levelsNatureMay 5, 2022Maria V. Yelshanskaya, Dhilon S. Patel, Christopher M. Kottke, Maria G. Kurnikova, Alexander I. Sobolevskythat contained 150 mM NaCl, 20 mM Tris-HCl pH 8.0, 1 mM βME and 1% digitonin (Cayman Chemical Company, 14952). Insoluble material was removed by ultracentrifugation (186,000g, 40 min). The supernatant was added

(3) Purification and cryo-EM structure determination of Arabidopsis thaliana GLR3.4STAR ProtocolsDecember 17, 2021Shanti Pal Gangwar, Marriah N. Green, Maria V. Yelshanskaya, Alexander I. SobolevskyFreestyle 293 expression medium,Gibco,Cat# 12338018 Sodium butyrate,Acros Organics,Cat# 263191000 Digitonin,Cayman Chemical Company,Cat#14952 Aprotinin,Sigma-Aldrich,Cat#A1153 Leupeptin,Sigma-Aldrich,Cat#L0649 Pepstatin A,Sigma-Aldrich,Cat#P4265 Kanamycin,Fisher

(4) Structure and desensitization of AMPA receptor complexes with type II TARP γ5 and GSG1LMolecular CellDecember 1, 2021Oleg Klykov, Shanti Pal Gangwar, Maria V. Yelshanskaya, Laura Yen, Alexander I. Sobolevskycontaining 150 mM NaCl, 20 mM Tris-HCl pH 8.0, 0.005% CHS and 0.05% digitonin (Cayman Chemical Company, 14952), and the protein was eluted using the same buffer supplemented with 2.5 mM D-desthiobiotin. To remove

(5) Structure of the Arabidopsis thaliana glutamate receptor-like channel GLR3.4Molecular CellAugust 1, 2021Marriah N. Green et al.containing 150 mM NaCl, 20 mM Tris-HCl pH 8.0, 1 mM βME and 1% digitonin (Cayman Chemical Company, 14952). Insoluble material was removed by ultracentrifugation (186,000 g, 40 min), while the supernatant was

(6) TRPV3 expression and purification for structure determination by Cryo-EMMethods in EnzymologyJune 1, 2021Arthur Neuberger, Kirill D. Nadezhdin, Alexander I. SobolevskyPepstatin A,Sigma,P4265 Strep-Tactin® Sepharose® (strep resin),iBa,2-1201-025 Digitonin,Cayman Chemical Company,14952 GDN101,Anatrace,1402423-29-3 Soybean Polar Lipid Extract,Avanti Polar Lipids,541602 Bio-Beads SM-2,Bio-Rad,152–8920 Critical

(7) Structures reveal gatekeeping of the mitochondrial Ca2+ uniporter by MICU1-MICU2eLifeJuly 15, 2020Chongyuan Wang, Agata Jacewicz, Bryce D Delgado, Rozbeh Baradaran, Stephen Barstow Long-D-glucopyranosyl-(1→3)-O-β-D-galactopyranosyl-(1→2)-O-[β-D-xylopyranosyl-(1→4)-β-D-galactopyranoside",Cayman Chemical Company,14952, "Chemical compound, drug",Membrane Scaffold Protein 1D1,Sigma,M6574, "Chemical compound, drug",5-Methyl-2-oxo-4-imidazo

(8) Allosteric AKT Inhibitors Target Synthetic Lethal Vulnerabilities in E-Cadherin-Deficient CellsCancers (Basel)September 13, 2019Nicola Bougen-Zhukov et al.USA). ARQ-092 (#21388), perifosine (#1008112), PHT-427 (#24188), staurosporine (#81590), digitonin (#14952), and FCCP (#15218) were purchased from Cayman Chemical. Oligomycin (#O4876), β-mercaptoethanol (#M3148),

(9) Mechanisms of Channel Block in Calcium-Permeable AMPA ReceptorsNeuronSeptember 1, 2018Edward C. Twomey, Maria V. Yelshanskaya, Alexander A. Vassilevski, Alexander I. Sobolevskysolubilized for two hours in 150 mM NaCI, 20 mM Tris-HCl pH 8.0, 1% digitonin (Cayman Chemical Company #14952). Insoluble material was removed by ultracentrifugation (40,000 rpm, 40 minutes). TALON cobalt-charged

(10) Tissue Damage Signaling Is a Prerequisite for Protective Neutrophil Recruitment to Microbial Infection in ZebrafishImmunityMay 15, 2018Cong Huang, Philipp NiethammerAcetylsalicylic acid (Aspirin),ACROS Organics,Cat#AC158180025 Cycloheximide,Sigma,Cat#01810 Digitonin,Cayman,Cat#14952 Dimethyl sulfoxide,Sigma,Cat#276855 ethyl 3-aminobenzoate methanesulfonate,Sigma,Cat#10521 Gentamycin,IBI

(11) Channel opening and gating mechanism in AMPA-subtype glutamate receptorsNatureSeptember 7, 2017Edward C. Twomey, Maria V. Yelshanskaya, Robert A. Grassucci, Joachim Frank, Alexander I. Sobolevskysolubilized for two hours in 150 mM NaCl, 20 mM Tris-HCl pH 8.0, 1% digitonin (Cayman Chemical Company #14952). Insoluble material was removed by ultracentrifugation (40,000 rpm, 40 minutes). Streptavidin-linked

(12) Cross-over endocytosis of claudins is mediated by interactions via their extracellular loopsPloS oneJanuary 1, 2017Gehne N, Lamik A, Lehmann M, Haseloff RF, Andjelkovic AV, Blasig IE.acetate, 20 mM HEPES, 2 mM MgCl2, pH 7.4). For permeabilization, 100 μM digitonin (Cayman Chemical, #14952) in KHM buffer was applied for 3 min; digestion was carried out using proteinase K (Thermo Fisher Scientific,

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Digitonin from Cayman Chemical

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Cayman Chemical

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Digitonin from Cayman Chemical

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